Global FISH Molecular Testing Market Expected to Reach US$978.6 Million by 2027 | CAGR: 7.2%: Astute Analytica

Astute Analytica research predicts revenue growth for Global Molecular FISH Testing Market from US$645.2M in 2021 to US$978.6M by 2027. The market registers a CAGR of 7.2% over the forecast period 2022-2027. The market is primarily driven by factors such as increasing prevalence of genomic abnormalities and cancers and increasing adoption of new molecular cytogenetic techniques.

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Market overview

Fluorescence in situ hybridization (FISH) is a molecular cytogenetics technique in which, using molecular probes, any type of chromosomal abnormality can be precisely encountered by hybridization. It was developed by biomedical researchers in the early 1980s to detect and locate the presence or absence of specific DNA sequences on chromosomes. FISH is often used to find specific features in DNA for use in genetic counseling, medicine, and species identification. Karyotyping takes at least 3-4 days to complete the whole process while FISH method is fast, one can get results within a day. Moreover, the cell culture process is not required to perform FISH, which is one of its most important advantages. Identification of specific chromosomal abnormalities, in particular structural and numerical; Chromosomal deletion, duplication and translocation can be detected using fluorescence in situ hybridization. By using variants like SKY and M-FISH, new non-random genetic abnormalities can also be identified. FISH can also be used to detect and locate specific RNA targets in cells, circulating tumor cells, and tissue samples.

Market dynamics

Drivers:

The increasing market momentum is attributed to factors such as increasing prevalence of genomic abnormalities and cancers and increasing adoption of new molecular cytogenetic techniques. Often, parents of children with developmental disabilities want to know more about their child’s conditions before choosing to have another child. These concerns can be resolved by analyzing the DNA of the parents and the child. In cases where the child’s intellectual disability is not understood, the cause of it can potentially be determined using FISH and cytogenetic techniques. Examples of diseases diagnosed using FISH include Prader-willi syndrome, Angelman syndrome, 22q13 deletion syndrome, chronic myeloid leukemia, acute lymphoblastic leukemia, velocardiofacial syndrome, and Down syndrome. Additionally, FISH can be used to establish a diagnosis, to assess prognosis, or to assess remission of a disease, such as cancer. The treatment can then be specifically adapted. Therefore, the demand for FISH probes in the medical sector has increased due to its function in analyzing biomarkers in tumor cells. Moreover, increasing adoption of new molecular cytogenetics techniques is also propelling the growth of the market. By using variants like SKY and M-FISH, new non-random genetic abnormalities can also be identified. Spectral karyotyping or multicolor FISH is a modification of native FISH in which, by using the different color sequence specific probe, each chromosome can be painted so, chromosomal rearrangement can be accurately encountered.

Constraints:

One of the biggest challenges in using FISH techniques is its high cost. The expense of performing an advanced FISH test with complicated image analysis could be over $200,000, hampering its adoption in research labs.

Opportunities:

Investments in pharmacogenomics and pharmaceutical research are expected to provide a lucrative opportunity for expanding the FISH molecular testing market.

Regional analysis

North America Dominates the Global FISH Molecular Testing Market

North America holds the highest share of the global molecular FISH testing market in 2021 and is further expected to maintain its dominance throughout the projection period. This is due to the increasing incidence of cancer and infectious diseases in the region. In addition, a considerable number of clinical research laboratories and academic institutes are also located in the region. The United States is the largest shareholder country in the FISH molecular testing market in North America, while Mexico registers the highest CAGR during the forecast period.

Germany is the top shareholder country in the European FISH molecular testing market in 2021

Europe holds the second highest share of the global molecular FISH testing market in 2021. Germany holds the highest share of the molecular FISH testing market in Europe in 2021 owing to the growing demand for point-of-care diagnostics. service and recent advances in pharmacogenomics. Based on probe type, the entire chromosome segment holds the highest market share in 2021. Additionally, cancer research is the highest application segment in the European FISH testing market molecules in 2021.

Asia-Pacific Region Holds Highest CAGR in Global Molecular FISH Testing Market

Asia-Pacific region registers the highest annual growth rate in the global molecular FISH testing market during the forecast period. This is due to the booming cytogenetics and molecular diagnostics industries in the region. Growing acceptance of new molecular cytogenetics techniques, increasing outsourcing operations and the need for early disease diagnosis and detection are expected to drive regional expansion. China is the largest shareholder country in APAC FISH molecular testing market in 2021. Based on technology, cryo FISH technology holds the highest share in APAC market in 2021.

South Africa dominates the FISH MEA molecular testing market

South Africa is the largest shareholder country in the FISH molecular testing market in the Middle East and Africa in 2021 and registers the highest CAGR over the projection period. This is due to a growing awareness of the benefits and potential of genetic testing among the MEA population. In terms of end users, the clinical segment holds the highest share in MEA’s FISH molecular testing market.

Brazil is the market leader in FISH molecular testing in South America

Brazil is the largest shareholder country in the FISH molecular testing market in South America in 2021 due to an increased interest of Brazilian researchers in new diagnostics, as well as the high prevalence of chronic diseases in the country. Based on applications, the cancer research segment holds the highest share in the FISH molecular testing market in South America. Additionally, the breast cancer research segment holds the highest share in the cancer research segment.

Competitive overview

Key players in the global FISH molecular testing market include Thermo Fisher, Abbott Laboratories, Agilent, Oxford Gene Technology, and ARUP Laboratories, among others.

Introduction to Segmentation

The following are the different segments of the global molecular FISH testing market:

Segment by Technology of the Global Molecular FISH Testing Market is sub-segmented into:

    • FISH flow
    • FISH
    • ImmunoFISH
    • Cryo FISH
    • Other FISH

By Probe Type, the Global Molecular FISH Testing Market segment is sub-segmented into:

    • Specific locus
    • Centromeric repeats
    • whole chromosome

By Cellular Stains segment of the global molecular FISH testing market is sub-segmented into:

    • DAPI (4,6-diamidino-2-phenylindole)
    • Acridine Orange
    • Others

Segment by Application of the Global Molecular FISH Testing Market is sub-segmented into:

    • Research against cancer
      • Lung
      • Breast
      • Bladder
      • Haematological
      • Gastric
      • Prostrate
      • Cervical
      • Other
    • Genetic diseases
    • Other

Segment by End User of the Global Molecular FISH Testing Market is sub-segmented into:

    • To research
    • Clinical
    • Companion diagnosis

By region Global Molecular FISH Testing Market Segment is sub-segmented into:

    • North America
    • Europe
    • Western Europe
      • Great Britain
      • Germany
      • France
      • Italy
      • Spain
      • Rest of Western Europe
    • Eastern Europe
      • Poland
      • Russia
      • Rest of Eastern Europe
    • Asia Pacific
      • China
      • India
      • Japan
      • Australia and New Zealand
      • ASEAN
      • Rest of Asia-Pacific
    • Middle East and Africa
      • United Arab Emirates
      • Saudi Arabia
      • South Africa
      • Rest of the Middle East and Africa
    • South America
      • Argentina
      • Brazil
      • Rest of South America

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